Can exaggerated response to a GH provocative test identify patients with partial GH insensitivity syndrome?

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منابع مشابه

Comparison between the growth response to growth hormone (GH) therapy in children with partial GH insensitivity or mild GH deficiency.

OBJECTIVES GH therapy is still controversial, except in severe GH deficiency (SGHD). The objective of this study was to compare the response to growth hormone (GH) therapy in children with partial GH insensitivity (PGHIS) and mild GH deficiency (MGHD) with those with SGHD. SUBJECTS AND METHODS Fifteen PGHIS, 11 MGHD, and 19 SGHD subjects, followed up for more than one year in the Brazilian pu...

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A girl with severe growth retardation had the clinical features of Laron syndrome. Her serum insulin-like growth factor-I level was completely unresponsive to exogenous GH administration. The serum GH-binding protein (GHBP) level was below the detectable limit in the patient, but it was normal in her parents and brother. Her parents and brother were normal in their height. Amplification with PC...

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ژورنال

عنوان ژورنال: European Journal of Endocrinology

سال: 2002

ISSN: 0804-4643,1479-683X

DOI: 10.1530/eje.0.1460319